Prefrontal dopamine and behavioral flexibility: shifting from an “inverted-U” toward a family of functions
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چکیده
منابع مشابه
Prefrontal dopamine and behavioral flexibility: shifting from an “inverted-U” toward a family of functions
Studies on prefrontal cortex (PFC) dopamine (DA) function have revealed its essential role in mediating a variety of cognitive and executive functions. A general principle that has emerged (primarily from studies on working memory) is that PFC DA, acting on D1 receptors, regulates cognition in accordance to an "inverted-U" shaped function, so that too little or too much activity has detrimental...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2013
ISSN: 1662-453X
DOI: 10.3389/fnins.2013.00062